An emergency warning for my friends and family, the UK is at risk of becoming a pariah bigger than China:
COVID-19 Useful Info
Saturday, March 27, 2021
WARNING: my fears about the over use of the vaccine may be materialising
Sunday, March 21, 2021
As immune escape becomes more widely known about I raise my concerns again about vaccinating too many people
I think it's ok vaccinating over 50s maybe over 40s because even if the immune escape happens we should see the virus out competed by a version that causes very mild or no symptoms.
Monday, March 8, 2021
Vit D what we know to date. Take supplements or get into the SUN!
It seems pretty clear to me that we should ensure we have adequate Vitamin D levels.
Tuesday, February 23, 2021
We will never wipe out COVID
Since we will never eradicate SARS-CoV-2 I am questioning whether we should be trying to vaccinate all adults.
My worry with the vaccination program is that the very infectious, although relatively mild current strains will be the ones which mutate to avoid the vaccines.
Conversely if we stick to vaccinating the vulnerable and NHS sapping demographic (50+) then the remainder of the population will be able to catch the virus and the virus strains which are as infections but LESS virulent (just cause a sniffle or no symptoms at all) will be the ones that out- compete the other.
It will then be those much less dangerous strains which circumvent the vaccine.
There is of course a very unlikely possibility that that crucible of healthy people might incubate a massively lethal mutant which is super virulent but also more infectious as in it doesn't affect or kill you until you've infected many people.
Maybe it's the fear of the later case that is driving the mass vaccination. I suspect however that it's more likely to save the economy.
Unfortunately it's possible it will do the exact opposite when new lockdowns are required due to emergence new vaccine evading variant which is still as virulent (or more) as the current strain.
Friday, October 23, 2020
Viral load Is almost certainly important
Circumstantial evidence is mounting that viral load (as we would expect from other viruses) is important.
Another Dr John special:
https://www.youtube.com/watch?v=NQ1h33mPGuU
What does this mean for us in everyday life, remembering the virus is largely transmitting through aerosol?
1) Ventilation is important
2) Hand shakes are best avoided - or wipe your hands on material afterwards
3) Masks remain important
4) Distance will help
Infection Fatality Rate Low - Evidence of my assumption at last
Dr. John Campbell give a good explanation of the WHO / Stanford Study.
NB for comparison Flu is about 0.04% to 0.1% annually (Ref: https://reason.com/2020/05/24/the-cdcs-new-best-estimate-implies-a-covid-19-infection-fatality-rate-below-0-3/).
Overall it's looking like if you are exposed to the virus your chance of death is statistically is very low:
0.23% (Median) which is lower than many Influenza viruses
Most areas will be more like 0.20%
People UNDER 70 range from 0% to 0.31% with a median of 0.05%
So if you are under 70 and healthy it is very low and about the SAME or less as Seasonal FLU
https://www.youtube.com/watch?v=ofGMSH5tjYk
The only 2 things I'd add are:
A) That Covid 19 is much more infectious than most seasonal flu so while the IFR is low it will results in more deaths than seasonal flu.
B) The inoculant (viral load / amount of virus) you get initially and subsequently will have a big impact on how ill you get and risk of death.
Monday, August 24, 2020
Reinfection from Covid proven
Friday, August 21, 2020
Way forward: living with Covid-19 for my friends and family
Whilst the governents are thrashing around unsure of what they should be doing I thought I'd put down my thoughts on what we should be doing to stay safe for those of us who aren't particularly vulnerable with kids.
I think the biggest issue facing society is how to 'unscare' everyone. I'm afraid that will largely fall to governments.
- Do children pass it to adults?
- Do children get it and quickly kill it or are they asymptomatic plague carriers (there is mounting evidence that they do carry larger viral loads however kids going back to school seemed to have little impact on Covid levels inthe UK)? See: https://www.cdc.gov/coronavirus/2019-ncov/hcp/pediatric-hcp.html
- Do pet animals pass it back to people (we know cats and dogs can get infected)
- What happened to the porton down report Matt Hanckock said would be published in May 2020? It was random sampling to see how many people had the virus or antibodies. See here: https://www.telegraph.co.uk/global-health/science-and-disease/coronavirus-tests-never-heard-hold-key-exit-lockdown/
Thursday, July 30, 2020
COVID-19 is Endemic and Winter is Coming!
“This infection is not going away, it’s now a human endemic infection,” Jeremy Farrar, Director of the Welcome Trust
This New Scientist Article explains
https://www.newscientist.com/article/2237475-covid-19-news-young-people-may-be-driving-spikes-in-cases-says-who/
It seems almost certain that colder weather will make COVID-19 worse as data is beginning to show:
https://covid.joinzoe.com/post/weather-covid
What do we do about it?
Well we have to come to terms with the facts:
1. We need to start living with the disease in the same way we live with seasonal flu (although it is much more dangerous)
2. We will need a vaccine regime for people at risk
3. We need to get Robust test & treatment regimes in place for everyone who asks for it (whether or not you have symptoms)
4. We cannot wipe this one out, even with a vaccine.
Tuesday, July 14, 2020
A COVID-19 Vaccine May Not Be the Answer
Basically, the common cold has just grown teeth and we have never developed a cure or vaccine for the common cold.
It seems like antibodies may not last long enough to make a vaccine useful except for very short term protection. My best guess is we are heading for mass vaccinations for all risk categories at critical times of year (e.g. UK winter). They will probably try and combine it with Flu vaccines (if it's safe to do so).
https://www.msn.com/en-gb/news/coronavirus/coronavirus-immunity-may-only-last-a-few-months-study-suggests/ar-BB16FXBD?ocid=msedgntp
Sunday, June 28, 2020
Masks - Do they help with COVID-19?
I am writing this because many people it seems are not clear on why face coverings are being made a legal requirement. If you want the headline then here it is - if you want more detail please read on.:
Face coverings and masks almost certainly help reduce the spread of COVID-19 (and other airborne viruses) but they only give limited protection to the person wearing the mask or covering.
Here is some useful info from the US CDC
https://www.cdc.gov/coronavirus/2019-ncov/prevent-getting-sick/cloth-face-cover.html
This is what the UK government tells you (Clear as to what you should do but suitably vague as to why!)
https://www.gov.uk/government/publications/staying-safe-outside-your-home/staying-safe-outside-your-home
As you read this please remember:
- COVID-19 is an Airborne Virus - that is to say, although it can be transmitted by touch the most dangerous and rapid transmission it has shown is because it travels in aerosol droplets which hover in the air for several minutes and via heavier droplets or gobbets of saliva which land on people from a cough or sneeze
- Having said that remember where your hands have been - have you touched your face/eyes/mouth or the outside of your mask? Or held a handle someone else has been touching?
- You can have no symptoms and still be highly infectious
- People with symptoms are also infectious
- Some people will only have mild symptoms or no symptoms but still have and be spreading COVID-19
- COVID-19 will, if like other similar viruses, deactivate within minutes of landing on cloth (the moisture it relies on gets absorbed into the cloth and all indications are that it requires the water to survive outside your body
- We don't have all the facts from studies yet so let us be cautious
After you read the rest of this post I hope you will take away the following tips:
- Face masks & coverings protect other people when you have symptoms
- Face masks & coverings may make you feel safer but they only give you limited protection in the case where someone breaths heavily or coughs/sneezed directly in your face
- Don't jog or bicycle right behind people even if they wear masks
- Masks are less important outside if you aren't going to be within 6 meters of people and if you do go withing 6 meters hold your breath until you pass
- Masks should be mandatory when you are indoors with strangers, colleagues or customers (not just)
- Avoid standing behind people with face masks
- Scarfs may actually be better than facemasks at protecting others
- If out and about and likely to be touching things other people have, carry sanitiser or sanitising wipes.
- Be careful removing your mask.
- If you have COVID-19 symptoms please don't go out wearing a mask thinking you are not going to infect people. If you have to for a critical health/safety-related reason a scarf may well be better but if possible use a respirator mask (note you don't need eye-coverings since you are protecting other people)
- Some people ask why the government isn't making it clear to people that masks are mainly about reducing spread by stopping the wearer spreading the virus. Well I can only guess but if I'm feeling generous I'd say they are hoping that if people believe they are protecting themselves they are more likely to wear them. Unfortunately, this has backfired in some cases as I hear people say (even in shops) - "Oh I'm bound to get it at some point, so I'll take the risk", "the horse has bolted" etc. perhaps not realising that they are significantly protecting customers in the case they have it but don't yet know.
- Some might say "If I'm at risk then I won't bother wearing a mask because it doesn't protect me much". While it's true it doesn't prevent aerosol inhalation some protection is better than none and it might trap that big glob of saliva with 100 billion virus particles in it that would have landed on your lips! That Might be the difference between mild symptoms on a worse case.
Here is a summary of what I believe various face coverings will do to help protect you and others (this is my OWN summary and is not the result of any study as there aren't any comprehensive ones around mask types like all of these):
Here is the more detailed info about why I believe the above statements are almost certainly correct.
General article from Cambridge University about helping prevent the spread:
https://www.cam.ac.uk/research/news/widespread-facemask-use-could-shrink-the-r-number-and-prevent-a-second-covid-19-wave-study
Royal Society Modelling study about why masks prevent the spread (and importantly might prevent larger particles with higher Covid "Doses" (Viral load in your infection will be reduced)):
https://royalsocietypublishing.org/doi/10.1098/rspa.2020.0376
Study showing cloth / surgical masks don't filter and it is probably the leakage around the edge of teh masks that causes MORE virus particles on the outside of the mack than in the inside when a wearer coughs.
https://www.acpjournals.org/doi/10.7326/M20-1342
Article showing how difficult this all is:
https://www.cidrap.umn.edu/news-perspective/2020/06/controversy-covid-19-mask-study-spotlights-messiness-science-during
Saturday, June 20, 2020
Vitamin D is important before you catch COVID19
https://youtu.be/qyMFsLFAE5o
Monday, May 25, 2020
Sunday, March 22, 2020
Info on COVID 19 for my friends & family (and anyone else)
I've put this together because I'm finding I'm repeating the same info to many people.
My headline is given the info we have at present we should assume this virus is an extremely infectious virus which is easily transmitted through the air in droplets from infected people’s sneezes, coughs AND breath and we should, therefore, reduce contact with people and keep away from places where may people have been.
Misinformation is also rife so I'm careful to draw out where I've made assumptions based on other viruses. The issue is that the scientific community doesn't like conjecture and like evidence and data. This is a problem when we aren't sure we have all the data and the stuff we do have may be misleading.
I'm relying most on the data coming out of Italy, Spain, France the UK and the USA are likely to be unadulterated. However, they too will only be as good as the testing the full picture in data is still missing.
Hopefully, the information below will help my friends & family understand why the authorities are taking such extreme measures. What I won’t attempt to do is comment on things like stockpiling and when it would be safe to start socialising again since these things really need to be managed by society and will need some of the questions I have answered.
I will add new blog posts and amend this one as more info comes to us.
Facts
1. We all know the disease is a Coronavirus - the same type as SARS & MERS.
2. It is, therefore, a respiratory disease.
3. It has spread more rapidly than people expected globally and in the UK (I think the establishment & scientists were expecting it to behave like SARS & MERS initially but it is likely down to the period which it is infectious before noticeable symptoms develop)
4. It definitely is more dangerous to older people (especially 70+)
5. It definitely is more dangerous to people with underlying medical conditions or who are pregnant
6. It definitely is less dangerous to younger people (especially people under 20)
7. Washing/sanitising hands is useful to kill the virus
8. Surgical masks (i.e. ones that don’t create an airtight seal around the nose and mouth) are not that useful unless you are infected or treating an infected person
9. People who die from the disease generally have the disease in the lungs (viral pneumonia – unlike bacterial type antibiotics have no effect)
10. People have a mild illness generally when the upper respiratory tract is infected
11. Secondary bacterial infections can complicate the disease but thankfully are mostly treatable with antibiotics
12. Some children have died from COVID-19
13. Some seemingly healthy people under 60 have died from the disease
14. Healthy people can often succumb because their immune system is overreacting (see cytokine storm mentioned later point iv) )
Pseudo Facts
These facts don't paint the full picture but are nevertheless bandied around a lot. They are mostly based on analysis of the data (which I've stated already is incomplete) and need much more investigation.
i) Other viruses (and almost certainly COVID-19) do not live long outside the body (minutes) UNLESS they are in droplets of water, saliva, mucus or other hydrating liquids. This means that cloths and absorbent material are VERY GOOD at destroying the thing. However hard surfaces can keep the virus alive for a long time (even several days)
ii) The death rate (Case Fatality Rate or CFR) for people known to be infected is estimated to be between 1% and 8%. This is really difficult to assess but regardless the authorities are more concerned with the rate of people needing hospital treatment and intensive care/ventilation
iii) Herd immunity would result in the virus dying out after 60 to 70% of the population of the UK has got it (note the UK govt had had to move from this approach because it would overload our health system). This is largely based on OTHER viruses but seems logical as long as there is little re-infection
iv) The disease can cause a cytokine storm where the body’s immune system produces far too many cytokines which trigger a massive response to the pathogen from the body’s defense cells. This can result in key bodily functions and organs being shut down and sometimes death and often lasting damage. (https://en.wikipedia.org/wiki/Cytokine_release_syndrome)
v) Surgical masks will not fully protect you in the presence of an infected person as air an droplets of liquid can be inhaled via the edges of the mask.
vi) Fully airtight masks (FFP3) are more effective but great care must be taken when removing them as they are likely to have viral particles on them
vii) Dogs and cats can catch the virus but we don’t know if they are infectious
viii) 20% of cases require hospital admission (not necessarily 20% of infected people as we DON'T know how many that is). I haven't managed my own sums but this is based on BBC stating around 4 in 5 cases may not need admission.
xi) Younger people make up a large number of hospital admissions. Whilst they aren't so likely to die, probably due to their strong immune systems younger people seem to form a large number of admissions (https://www.washingtonpost.com/health/2020/03/19/younger-adults-are-large-percentage-coronavirus-hospitalizations-united-states-according-new-cdc-data/)
Unsubstantiated Information
This is information I've gleaned from sources (all mentioned) but which we do not have the data to confirm or deny. We should not ignore the risks that these points imply – I’ve only added ones I think are likely to be true and a high impact if they are true.
1. Re-infection by the virus is possible and indeed *may* cause a worse outcome as re-infection may have increased risk of causing a cytokine storm in the individual
2. Ibuprofen can significantly worsen the disease and outcomes (https://www.npr.org/sections/health-shots/2020/03/18/818026613/advice-from-france-to-avoid-ibuprofen-for-covid-19-leaves-experts-baffled?t=1584882911715)
3. Drinking plenty of liquid when you have a mild version of the virus (in the upper respiratory tract) can help wash the virus down to the stomach and stop running out of control and ending up in the lungs. This seems possible but a bit unlikely however staying hydrated is very important so do it anyway even if you don’t have the virus
4. Many more people currently have it than the government expects due to the long period people do not exhibit symptoms. This will be even worse if it turns out a substantial number of people never display symptoms.
Questions which we need answering ASAP
and assumptions I suggest we make whilst they remain unanswered
A) Is the disease mainly spread through the Aerosol effect? [ASSUME: this IS the case hence the UK govt encouraging people to stay meters apart – although this will not be enough in many cases as the aerosol effect means particles can hang in the air for a period of time]
B) We need evidence whether people can carry the virus and spread it whilst remaining largely asymptomatic without ever displaying significant symptoms. This especially applies to kids. If so what proportion of infections do we think this applies to? [ASSUME: this IS the case and that people who are well maybe infectious so keep our distance]
C) What is the genuine length of time people are infectious whilst asymptomatic?
D) Can re-infection occur? [ASSSUME: Some level of re-infection is possible and so if you get COVID-19 put yourself in the AT RISK category afterwards until we have more information)
E) Does a re-infected person spread the disease? [ASSUME: they do until we hear otherwise]
F) Can re-infection cause worse outcomes due to the body overacting to the pathogen it recognised? [ASSUME: it does do until we hear otherwise]
G) Can Ibuprofen (eg Nurofen) make the disease worse? [ASSUME: Until we have more info if your doctor hasn’t prescribed Ibuprofen I would stick to paracetamol on the off-chance. To me it seems likely that there could be an issue here especially for diabetics or people with hypertension (as in UK govt advice: https://www.gov.uk/government/news/ibuprofen-use-and-covid19coronavirus)
H) Can animals catch the virus – especially dogs and cats? If this is the case then we need to find out very quickly if they can infect people and hence cause an animal reservoir of the disease ) https://www.afcd.gov.hk/english/publications/publications_press/pr2346.html?mod=article_inline). [ASSUME: I think we are fairly safe to assume reinfection from animals is not like to be a serious problem at the moment]
Useful Reading
Guardian Article on some Myths debunked (I agree with most):
https://www.theguardian.com/world/2020/mar/21/can-face-mask-protect-me-coronavirus-covid-19-myths-busted
Lancet letter which triggered concern over Ibuprofen
https://www.thelancet.com/action/showPdf?pii=S2213-2600%2820%2930116-8
Article on Aerosol Transmission vs Surface transmission
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3682679/
NHS Guidance on When You need to use FFP3 masks (i.e. with coronavirus)
https://www.rdash.nhs.uk/wp-content/uploads/2017/08/Appendix-47-Surgical-Face-Mask-FFP3.pdf
National Geographic article from Feb 2020 about how the virus damages patients.
https://www.nationalgeographic.co.uk/science-and-technology/2020/02/heres-what-coronavirus-does-body